How can bioinformatics help me?

There are a huge number of programs and databases which can help you analyse your sequence, find similar sequences, looking for mapping and genetic diseases, look for bibliographic references etc.

I've seen a program that does what I want, how can it be made available?

Please give us some detail of the program,for example: Reference, address of author, conditions of release, etc. And we will try ,but NOT guarantee, to meet all requests for new software.If we can`t do it,we will consider all requests and suggest a program we already have which performs an equivalent function.

Can I copy some program from CBI?

The software which is under licence isnot permited to copy,but free softwares are available from CBI via anonymous ftp.

How do I run a program and then log out and leaving it running under Linux/Unix OS?

Run the program in background, or you can use screen. This is often very easy to do.

How can I quickly compare all my sequences?

The easiest way is to use edialign (Local multiple alignment of sequences), EMMA (interface to ClustalW program), infoalign (Information on a multiple sequence alignment), plotcon (Plot quality of conservation of a sequence alignment), prettyplot (Displays aligned sequences, with colouring and boxing), showalign (Displays a multiple sequence alignment) or tranalign (Align nucleic coding regions given the aligned proteins) in WebLab.

How can I search for Motifs in my sequences?

You can use patmatdb (Search a protein sequence with a motif), dreg (Regular expression search of a nucleotide sequence) or patmatmotifs (Search a PROSITE motif database with a protein sequence) etc. in WebLab.

How can I search for repeats in my sequences?

You can use RepeatMasker. RepeatMasker is a program that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). On average, almost 50% of a human genomic DNA sequence currently will be masked by the program. Sequence comparisons in RepeatMasker are performed by the program cross_match, an efficient implementation of the Smith-Waterman-Gotoh algorithm developed by Phil Green. (from http://www.repeatmasker.org/)