Xiaocheng Gu, Professor

Professor emeritus
Center for Bioinformatics
Life Science College
Peking University

Contact

E-mail:

Address

Room 609
New Life Science Building
Peking University
Beijing, P. R. China,
100871

Degrees, Qualifications:

• 1984-1985 Visitor, in Department of Biological Chemistry, Harvard Medical School
• 1961-1964 Advanced training on Protein Crystallography in Department of Chemistry, Peking University
• 1948-1952 Graduated from the Department of Plant Sciences, Peking University

Work Experience

• 1995- present : Professor emeritus, College of Life Sciences, Peking University
• 1995 - 2005 : Coordinator, CUSBA Program
• 1997 - 2004 : Chairperson, Council of Scientific Advisors, ICGEB
• 1994 - 2004 : Chairperson, Council of Academic Committee, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University?
• 1995 - 1997 : Member, Council of Scientific Advisors, ICGEB (International Center for Genetic Engineering and Biotechnology)
• 1992 - 1995 : Professor of Biophysics, College of life Sciences, Peking University
• 1986 - 1995 : Member and Director of the Evaluation Group for Section of Biochemistry and Molecular Biology, the Chinese National Science Foundation
• 1986 - 1995 : Member,. Working Group for establishment of the Biotechnology Area in the National High Technology and Development (863) Program; Director, Experts Group for Section of Protein Engineering, 863 Program ; Member, Experts Committee for the Biotechnology Area, 863 Program
• 1952 - 1995 : Teaching assistant, lecturer, associate professor and professor in Department of Biology, Peking University
• 1987 - 1994 : Director, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University
• 1985 - 1992 : Chairperson, Department of Biology, Peking University
• 1981 - 1989 : Coordinator, CUSBEA Program for Ministry of Education
• 1978 - 1984 : Deputy chairperson, Department of Biology, Peking University

National Honors and Awards

• 2000 : National First Prize for Excellent Performance in the Biotechnology Area of the 863 Program, from the Ministry of Science and Technology
• 1994 : The Golden Ox Prize of the State Planning Commission for the National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University?
• 1993 : National Second Prize for Excellent Performance in the Biotechnology Area of the 863 Program, from the Ministry of Science and Technology
• 1991 : National Award for Excellent Performance in the Biotechnology Area of the 863 Program, from the Ministry of Science and Technology
• 1990 : The Golden Ox Prize of the State Planning Commission, for the National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University
• 1989 : Listed in the International Who is Who
• 1986 : First Prize for Progress in Science and Technology from the Ministry of Education ; Studies on the Biology of the Giant Panda (Group Award)
• 1982 : National Second Prize for Natural Science Research : Crystal Structure Analysis of the Rhombohedral 2 Zinc Porcine Insulin Molecule (Group Award)
• 1979 : National 3-8 Award for Career Women
• 1978 : National Award from the National Congress of Science and Technology, for "Crystal Analysis of the Insulin Molecule" (Group Award)

Publications

• The Insulin Structure Group?The Rhombohedral 2 Zinc Porcine Insulin Molecule at 1.8 Angstrom Resolution, (1974), Scientia Sinica restarted, Vol.1
• "Protein Engineering" Gu Xiaocheng in <Biotechnology> Ed: Gu Xiaocheng (1994)?Shanghai Science andTechnology Press
• "Protein Engineering" Gu Xiaocheng in <Turn of the Century : Dialogue with Hi-Tech Experts> Edited by Zhu Lilan, Vice Minister of the Ministry of Science and Technology and Foreword by BB Ghali, Secretary General of the UN (1995) LiaoNing Press
• YX Qu, SP Liang,JZ Ding, L Ma, RJ Zhang, XC Gu, Proton Nuclear Magnetic Resonance Studies on Huwentoxin I from the Venom of the Spider Selenocosmia huwena : Sequence specific H-NMR Assignments 1995 J Prot. Chem. 14 : 549-557
• YX Qu, SP Liang,JZ Ding, XC Liu, RJ Zhang, XC Gu, Proton Nuclear Magnetic Resonance Studies on Huwentoxin-I from the Venom of the Spider Selenocosmia huwena.: 2 Three Dimensional Structure in Solution 1996 J Prot. Chem 16: 565-574
• J Zhang, ZQ Hua, JRH Tame, GY Lu, RJ Zhang, XC Gu, The Crystal Structure of High Oxygen Affinity Species of Haemoglobin (Bar-Headed Goose Haemoglobin : The Oxy Form ) 1996 J Mol. Biol. 255 : 484-493
• GY Lu, ZH Zhou, ML Breiber, J Jakana, DY Cai, XC Wei, SC Chen, XC Gu, W Chiu,, Structure of Double-Shelled Rice Dwarf Virus, 1998, J Virol, 72 : 8541-8546
• SY Lu, SP Liang,XC Gu, Three dimensional Structure of Selenocosmia huwena Lectin-I (SHL-I) From the Venom of the Spider Selencosmia huwena by 2D NMR, 1999, J Prot Chem.18 : 609-617
• SY Lu, PC Deng, XC Liu, JC Luo, RS Han, XC Gu, SP Liang, XC Wang, F Li, V Lozanov, A Patthy, S Pongor, Solution Structure of the Major-Alpha-Amylase Inhibitor of the Crop Plant Amaranth, 1999, J Biol. Chem. 274 : 20473-20478
• HT Ding, H Ren, Q Chen, G Fang, LF Li, R Li, Z Wang, XY Jia, YH Liang, MH Hu, Y Li, JC Luo, XC Gu, XD Su, M Luo, SY Lu, Parallel Cloning, Expression, Purification and Crystallization of Human Proteins for Structural Genomics, 2002, Acta Cryst D58:2102-2108
• DL Li,YC Xiao, X Xu, X Xiong, SY Lu, ZH Liu, Q Zhu, MC Wang, XC Gu, SP Liang, Structure-Activity Relationship of HinanToxin –IV and Structure Determination of Active and Inactive Sodium Channel Blockers, 2004, J Biol. Chem. 279 : 37734-37740
• XY Dai,Q Chen, M Lian, YZ Zhou, SY Lu, YJ Chen, JC Luo, XC Gu, Y Jiang, M Luo, XF ZhengSystematic High-yield Production of Human Secreted Proteins in E. Coli, 2005, BBRC 332 : 593-601
• Q Chen, YH Liang,XD Su, XC Gu, XF Zheng, M Luo, Novel IMP Binding in Feedback Inhibition of Hypoxanthin Guanine Phosphoribosyl Transferase from Thermoanaerobacter tengcongensis, 2005, J Mol. Biol, 348 : 1199-1210
• Guo A, He K, Liu D, Bai S, Gu X, Wei L, Luo J, DATF : A Database of Arabidopsis Transcription Factors, 2005, Bioinformatics, 21 : 2568-2569
• Gao G, Zhang Y, Guo A, Zhu Q, Tang W, Zheng W, Gu X, Wei L, Luo J, DRTF: A Database of Rice Transcription Factors, 2006, Bioinformatics, 22 : 1286-1287
• Xiaofeng Zheng, Xueyu Dai, Yanmei Zhao, Qiang Chen, Fei Lu, Deqiang Yao, Xinping Liu, Chuanmao Zhang, Xiaocheng Gu, Ming Luo, Restructuring of the Dinucleotide Binding Fold in a NADP(H) Sensor Protein, 2007, PNAS, 104 : 8809-8814
• Chuan-Yun Li, Quan Yu, Zhi-Qiang Ye, Ying Sun, Quanyue He, Xiao_Mo Li, Wuxue Zhang, Jingchu Luo, Xiaocheng Gu, Xiaofeng Zheng, Liping Wei, A Nonsynonomous SNP in Human Cytosolic Sialidase in a Small Asian Population Results in Reduced Enzyme Activity : Potential Link with Severe Adverse Reactions to Oseltamivir, 2007, Cell Research, 17 : 357-362